The technique of EBUS-TBNA has rapidly developed over recent years. However, to the best of our knowledge, no previous study has investigated whether or not CT-based texture analysis can be used to discriminate between the mediastinal lymphadenopathy of sarcoidosis and that of SCLC.Įndobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) is an important option for the histopathological evaluation of mediastinal lymphadenopathy. Although a limited number of published articles are available, the potential of CT-based texture analysis as a new imaging approach for distinguishing between benign and malignant lesions in the lung and mediastinum has gradually been recognized. Texture analysis of chest CT data has been used for images of benign and malignant lung lesions and mediastinal lymphadenopathy associated with various diseases. In such cases, distinguishing benign from malignant diseases by computed tomography (CT) or even by 18F-fluorodeoxyglucose positron emission tomography/CT (FDG-PET/CT) is difficult. For example, small cell lung cancer (SCLC) metastases and sarcoidosis are typical diseases that sometimes involve mediastinal lymph nodes without manifesting obvious lung lesions. In daily clinical care for mediastinal lymphadenopathy, it is relatively common that no abnormal lesions are seen in the lung field, whereas multiple enlarged lymph nodes are observed in the mediastinum. The causes of mediastinal lymphadenopathy are diverse, and include malignant diseases such as lung cancer and malignant lymphoma and benign diseases such as sarcoidosis and inflammation/infection. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: All relevant data are within the manuscript and its Supporting Information files.įunding: The authors received no specific funding for this work.Ĭompeting interests: The authors have declared that no competing interests exist. Received: AugAccepted: NovemPublished: December 2, 2020Ĭopyright: © 2020 Koda et al. Eapen, University of Texas MD Anderson Cancer Center, UNITED STATES

(2020) CT texture analysis of mediastinal lymphadenopathy: Combining with US-based elastographic parameter and discrimination between sarcoidosis and lymph node metastasis from small cell lung cancer. Citation: Koda E, Yamashiro T, Onoe R, Handa H, Azagami S, Matsushita S, et al.

Mugshots recent arrests